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5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Mutations, Blood

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Updated Test Information:

Test Description
5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Mutations, Blood
Synonym(s)
MTHFR 2 Mutations Analysis
Test ID
MTHP
General Information
Useful for:
Direct mutation analysis for the MTHFR C677T and/or A1298C mutations should be reserved for patients with coronary artery disease, acute myocardial infarction, peripheral vascular artery disease, stroke, or venous thromboembolism who have increased basal homocysteine levels or an abnormal methionine-load test
Specimen Type
Whole Blood
Specimen Requirements
Yellow
Stability
Ambient (preferred) 7 days
Frozen 14 days
Refrigerated 14 days
Unacceptable Specimen Conditions
Gross hemolysis OK
Gross lipemia OK
Other Extracted DNA
Methodology
Direct Mutation Analysis
Estimated TAT
3-5 days
Testing Schedule
Monday-Friday
Test Includes
MTHFR MTHFR C677T Mutation Analysis
MTHAC MTHFR A1298C Mutation Analysis
CPT Code(s)
81291x2
Minimum Sample Volume
1 mL blood in a 3 mL ACD tube
Reference Range
Negative
Performing Lab
Mayo
LOINC Code(s)
28005-7, 28060-2, 69047-9, 69049-5, 18771-6