Myeloperoxidase AntibodyPrint this page
Updated Test Information:
MPO, ANCA, Antineutrophil cytoplasmic autoantibodies
Myeloperoxidase (MPO) antibodies are useful in the diagnosis and disease management of patients with primary systemic small vessel vasculitides. Elevated levels of MPO are found during active phases of the disease and lower during remission. Assay results should be used in conjunction with clinical findings and other serological tests.
|Alternate Specimen Type||
Plasma (Li-Heparin, EDTA, or Citrate)
|Additional Processing Details||
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.
|Unacceptable Specimen Conditions||
Lipemic, hemolyzed or microbially contaminated samples.
Fluorescent enzyme immunoassay (FEIA)
Monday-Saturday, alternating days
|Minimum Sample Volume||
|Pediatric Min. Volume (if applicable)||
Negative < 3.5 U/mL
Equivocal 3.5-5.0 U/mL
Positive > 5.0 U/mL