Laboratory Services

Varicella-Zoster Antibody, IgG, Serum

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Updated Test Information:

Test Description
Varicella-Zoster Antibody, IgG, Serum
Synonym(s)

Chickenpox; Herpes Zoster Antibodies; Shingles; Varicella-Zoster Antibody Screen, Qualitative, Serum; Varicella-Zoster Immune Status, Serum; VZ Ab, IgG; VZV; Varicella-Zoster IgG, Serum

Test ID
VZPG
General Information

Useful for:



  • Determination of immune status of individuals to the varicella-zoster virus (VZV)

  • Documentation of previous infection with VZV in an individual without a previous record of immunization to VZV

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel (SST)

  • Acceptable: Red Top

Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 14 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat-inactivated specimen

Limitations

  • IgG-class antibodies to varicella-zoster virus may be present in serum specimens from individuals who have received blood products within the past several months but have not been immunized or experienced past infection with this virus

  • Serum specimens drawn early during acute phase of infection may be negative for IgG-class antibodies to this virus.

Methodology

Multiplex Flow Immunoassay (MFI)

Estimated TAT

1-3 days

Testing Schedule

Monday-Saturday

Retention

14 days

CPT Code(s)

86787

Additional Information
Minimum Sample Volume

0.4 mL

Reference Range

  • Vaccinated: Positive (≥ 1.1 AI)

  • Unvaccinated: Negative (≤ 0.8 AI)


Performing Lab

Mayo

LOINC Code(s)

15410-4, 5403-1