Vasculitis (ANCA) PanelPrint this page
Updated Test Information:
Vasculitis (ANCA) Panel
Antineutrophil cytoplasmic autoantibodies, MPO, PR3, GBM, Goodpasture Syndrome
Antineutrophil cytoplasmic antibodies (ANCA) are autoantibodies found in patients with primary systemic small vessel vasculitides associated diseases such as Wegener granulomatosis (WG), microscopic polyangiitis (MPA), Anti-GBM (Goodpasture’s syndrome) and eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome). ANCA’s have been found to be useful in diagnosing and monitoring inflammatory activity in suspected vascular diseases. Assay results should be used in conjunction with clinical findings and other serological tests.
|Alternate Specimen Type||
Plasma (Li-Heparin, EDTA, or Citrate)
|Additional Processing Details||
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.
|Unacceptable Specimen Conditions||
Lipemic, hemolyzed or microbially contaminated samples.
Fluorescent enzyme immunoassay (FEIA)
Monday-Saturday, alternating days
Proteinase 3 Antibody
Glomerular Basement Membrane Antibody
|Minimum Sample Volume||
|Pediatric Min. Volume (if applicable)||
6969-0, 6968-2, 49774-3