Test Directory

CAIX

Clone:

MRQ-54 (Spokane)

Synonym(s):

Carbonic Anhydrase 9 (IX)

Application:

Positive in clear cell renal cell carcinoma and can be used for diagnosis of primary renal cell carcinoma and metastatic disease.  Also, it has been shown to be positive in a subset of breast cancers, brain tumors, head and neck cancers, and stomach cancers.  

Specimen Type:

Formalin-fixed, paraffin-embedded tissue blocks (FFPE). If tissue blocks are not available, unstained slides are acceptable (please submit 1–2 slides per antibody to be tested, cuts must be 4 microns thick).

Collection Procedure:

Tissue removed during a surgical procedure and placed in 10% NBF soon after removal from the patient. Appropriate tissue for requested staining.

Required Information:

Complete the Incyte Diagnostics requisition with the patient's demographics and relevant clinical history.

Specimen Stability:

Ambient: Indefinite

Unacceptable Specimen:

Slides or paraffin blocks with no tissue remaining. Samples fixed in fixatives other than 10% neutral buffered formalin. Paraffin blocks that have been overheated or frozen.

Department:

Histology

Method:

IHC, Ventana Ultra Stainer

Turnaround:

12 business days from receipt

Performed:

Monday–Saturday

Retention:

Blocks: 10 years
Slides: 10 years

CPT Code:*

88341
88342

*The listed CPT codes are for reference use only. Final coding is based on CPT guidelines and individual circumstances.

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