HER-2 fluorescence in situ hybridization, HER2/Neu by FISH
HER-2 gene amplification in formalin fixed, paraffin embedded tissues, usually human breast tissue. HER-2 FISH results correlated with clinical and pathological information can be used as a prognostic tool for stage II, node positive breast.
Formalin-fixed, paraffin-embedded tissue blocks (FFPE). If tissue blocks are not available, unstained slides are acceptable (please submit 1-2 slides per antibody to be tested, cuts must be 4 microns thick).
Tissue removed during a surgical procedure and placed in 10% NBF soon after removal from the patient. Appropriate tissue for requested staining.
Complete the Incyte Diagnostics requisition with the patient's demographics and relevant clinical history.
Ambient: Indefinite as paraffin block; 6 weeks for recut slides
Slides or paraffin blocks with no tissue remaining. Samples fixed in fixatives other than 10% neutral buffered formalin. Paraffin blocks that have been overheated or frozen.
Abbott/Vysis, immunofluorescence, DNA probes
*The listed CPT codes are for reference use only. Final coding is based on CPT guidelines and individual circumstances.