Test Directory

17-Hydroxyprogesterone, Serum

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Updated Test Information:

Test Description
17-Hydroxyprogesterone, Serum
Synonym(s)
17-Hydroxyprogesterone
Test ID
OHPG
General Information
Useful for:
The analysis of 17-hydroxyprogesterone (17-OHPG) is 1 of the 3 analytes along with cortisol and androstenedione, that constitutes the best screening test for congenital adrenal hyperplasia (CAH), caused by either 11- or 21-hydroxylase deficiency.
Analysis for 17-OHPG is also useful as part of a battery of tests to evaluate females with hirsutism or infertility; both can result from adult-onset CAH
Specimen Type
Serum
Specimen Requirements
Red Top
Stability
Refrigerated (preferred) 14 days
Frozen 28 days
Ambient 7 days
Unacceptable Specimen Conditions
Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Other Serum gel tube
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
NY State Available
Yes
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Estimated TAT
2-5 days
Testing Schedule
Monday-Friday
CPT Code(s)
83498
Minimum Sample Volume
0.25 mL
Reference Range

CHILDREN
Preterm infants
Preterm infants may exceed 630 ng/dL, however, it is uncommon to see levels reach 1,000 ng/dL.

Term infants
0-28 days: <630 ng/dL
Levels fall from newborn (<630 ng/dL) to prepubertal gradually within 6 months.

Prepubertal males: <110 ng/dL
Prepubertal females: <100 ng/dL

ADULTS
Males: <220 ng/dL
Females
Follicular: <80 ng/dL
Luteal: <285 ng/dL
Postmenopausal: <51 ng/dL

Performing Lab
Mayo
LOINC Code(s)
1668-3