Laboratory Services

Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum

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Updated Test Information:

Test Description
Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Synonym(s)

Acetylcholine Receptor (Muscle AChR) Antibodies, AChR (Acetylcholine Receptor), Anti -Neuromuscular Junction Receptor Antibodies, Myasthenia Gravis Antibodies

Test ID
ARBI
General Information

Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children


 Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders


 An adjunct to the test for P/Q-type calcium channel binding antibodies as a diagnostic aid for Lambert-Eaton myasthenic syndrome

Container Type

Red top

Specimen Type

Serum

Specimen Requirements

1.5 mL

Specimen Collection / Processing Instructions

Centrifuge and aliquot serum into a plastic vial For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.

Minimum Sample Volume

1 mL

Stability

Refrigerated (preferred) 28 days
Frozen 28 days
Ambient 72 hours

Unacceptable Specimen Conditions

Gross hemolysis, gross lipemia, gross icterus

Methodology

Radioimmunoassay (RIA)

Estimated TAT

3 to 6 days

Testing Schedule

Monday through Sunday

Retention

28 days

CPT Code(s)

86041

Reference Range

< or =0.02 nmol/L

Performing Lab

Mayo

LOINC Code(s)

97558-1