Laboratory Services

Alpha-Subunit Pituitary Tumor Marker, Serum

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Updated Test Information:

Test Description
Alpha-Subunit Pituitary Tumor Marker, Serum

Alpha Glycoprotein Subunit, Alpha Subunit, HCG, Alpha-HCG (Human Chorionic Gonadotropin), Alpha-PGH (Pituitary Glycoprotein Hormone), Alpha-Subunit of Pituitary Glycoprotein Hormones (Alpha-PGH), Serum, Chorionic Gonadotropins, Alpha-Subunit, Glycoprotein Subunit, HCG, Alpha Subunit, Hormone, Alpha-Subunit, PGH (Pituitary Glycoprotein Hormone), Pituitary Glycoprotein Alpha Subunit, Pituitary Gonadotropins, Alpha-Subunit

Test ID
General Information

Adjunct in the diagnosis of pituitary tumors

As part of the follow-up of treated pituitary tumor patients

Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance

Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism

Container Type


Specimen Type


Alternate Specimen Type

Red Top

Specimen Requirements

1 mL

Specimen Collection / Processing Instructions

Centrifuge and aliquot serum into a plastic vial

Minimum Sample Volume

0.35 mL


Frozen (preferred) 90 days
Refrigerated 7 days 

Unacceptable Specimen Conditions

Gross hemolysis


Immunochemiluminescent Assay

Estimated TAT

2 to 8 days

Testing Schedule



3 months

CPT Code(s)


Reference Range


< or =5 days: < or =50 ng/mL

6 days-12 weeks: < or =10 ng/mL

3 months-17 years: < or =1.2 ng/mL

Tanner II-IV*: < or =1.2 ng/mL


Males: < or =0.5 ng/mL

Premenopausal females: < or =1.2 ng/mL

Postmenopausal females: < or =1.8 ng/mL

Pediatric and adult reference values based on Mayo studies.

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/-2) years and for girls at a median age of 10.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

Performing Lab


LOINC Code(s)