Test Directory

Diphtheria/Tetanus Antibody Panel, Serum

Print this page

Updated Test Information:

Test Description
Diphtheria/Tetanus Antibody Panel, Serum
Synonym(s)

Anti-tetanus toxoid; C. tetani; Clostridium tetani; Corynebacterium diphtheriae Antitoxin; Diphtheria Antitoxoid; Tetanus Immune Response; Tetanus toxoid antibodies; Tetanus/Diphtheria Antibody Panel

Test ID
DTABS
General Information

Useful for:



  • Assessment of an antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization

  • Aids in the evaluation of immunodeficiency

  • This test should not be used to diagnose tetanus infection

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel

  • Acceptable: Red Top

Stability

  • Refrigerated (preferred):30 days

  • Frozen: 30 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat Inactivated specimen

Limitations

  • This assay does not provide diagnostic proof of lack of protection again diphtheria or the presence of absence of immunodeficiency. Results must be confirmed by clinical findings and other serological tests

  • The diagnosis of tetanus is by clinical observation. A positive wound culture for the agent of tetanus, Clostridium tetani, may support, but does not confirm, the diagnosis. Toxin assays for tetanospasmin may be useful but are only available in a few laboratories

  • The results obtained from this assay are not diagnostic proof of lack of protection against tetanus or the presence or absence of immunodeficiency

Methodology

Enzyme Immunoassay (EIA)

Estimated TAT

1-4 days

Testing Schedule

Monday-Friday

Test Includes

  • Diphtheria IgG Ab

  • Diphtheria IgG Value

  • Tetanus IgG Ab

  • Tetanus IgG Value

Retention

14 days

CPT Code(s)

86317x2

Additional Information
Minimum Sample Volume

0.8 mL

Reference Range
Assay Patient Status Interpretation (IU/mL)
DIPHTHERIA TOXOID IgG ANTIBODY Vaccinated Positive (≥ 0.01)
Unvaccinated Negative (< 0.01)
TETANUS TOXOID IgG ANTIBODY Vaccinated Positive (≥ 0.01)
Unvaccinated Negative (< 0.01)
Performing Lab

Mayo

LOINC Code(s)

33469-8, 45166-6, 48654-8, 53935-3