dsDNA AntibodyPrint this page
Updated Test Information:
Double stranded DNA, ANA, Antinuclear Antibodies, Anti-DNA
dsDNA antibodies are a disease specific serological marker for the diagnosis and disease management of patients with systemic lupus erythematosus (SLE). More than 90% of sera from patients with active SLE contain dsDNA antibodies. Smaller amounts may be present in patients with other rheumatic disorders, chronic active hepatitis, infectious mononucleosis, and biliary cirrhosis. Assay results should be used in conjunction with clinical findings and other serological tests.
|Alternate Specimen Type||
Plasma (Li-Heparin, EDTA, or Citrate)
|Additional Processing Details||
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.
|Unacceptable Specimen Conditions||
Lipemic, hemolyzed or microbially contaminated samples.
Fluorescent enzyme immunoassay (FEIA)
Monday-Saturday, alternating days
|Minimum Sample Volume||
|Pediatric Min. Volume (if applicable)||
Negative < 10 IU/mL
Equivocal 10-15 IU/mL
Positive > 15 IU/mL