Laboratory Services


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Updated Test Information:

Test Description

Epidermal Growth Factor Receptor

General Information

Epidermal Growth Factor Receptor (EGFR) overexpression can occur in a variety of tumor types, including breast, prostate, ovarian, brain, lung and predominantly squamous cell carcinomas. Tumors that express EGFR are associated with a poor prognosis and a shorter disease-free survival. Most colon carcinomas will show expression of EGFR in more than 1% of the invasive tumor cells. Patients whose tumor expresses EGFR are eligible for cetuximab therapy although the response to therapy is independent of the intensity or percentage of cells staining.

Specimen Type

  • A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type

  • One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered

  • Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Required Information

Complete the Incyte Diagnostics requisition with the patient's demographics and relevant clinical history.


Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.


Immunohistochemistry (IHC)

Estimated TAT

3 Days

CPT Code(s)


Performing Lab

NeoGenomics Laboratories