Laboratory Services

Epstein-Barr Virus DNA Detection and Quantification, Plasma

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Updated Test Information:

Test Description
Epstein-Barr Virus DNA Detection and Quantification, Plasma

EBV DNA, EBV, EBV DNA level, EBV DNA PCR, EBV DNA quant, EBV PCR, EBV quant, EBV viral load, Epstein-Barr virus, Infectious mononucleosis, PTLD

Test ID
General Information

Diagnosis of Epstein-Barr virus (EBV)-associated infectious mononucleosis in individuals with equivocal or discordant EBV serologic marker test results

Diagnosis of post-transplant lymphoproliferative disorders (PTLD), especially in EBV-seronegative organ transplant recipients receiving antilymphocyte globulin for induction immunosuppression and OKT-3 treatment for early organ rejection

Monitoring progression of EBV-associated PTLD in organ transplant recipients

This test should not be used to screen asymptomatic patients.

This assay detects and quantifies the level of Epstein-Barr virus (EBV) DNA present in the plasma of organ transplant recipients who are at risk of developing EBV-associated post-transplant lymphoproliferative disorder and in individuals with infectious mononucleosis. The assay is calibrated to the First World Health Organization International Standard for EBV for nucleic acid amplification techniques.

Container Type

Lavender Top

Specimen Type

Plasma EDTA

Specimen Requirements

1.5 mL

Specimen Collection / Processing Instructions

Centrifuge blood within 2 hours of collection and aliquot plasma into a plastic vial

Minimum Sample Volume

0.5 mL


Frozen (preferred) 84 days
Refrigerated 6 days


Real-Time Polymerase Chain Reaction (RT-PCR)

Estimated TAT

1 to 3 days

Testing Schedule

Monday through Saturday


30 days

CPT Code(s)


Reference Range


STAT Orderable (Y/N)


Performing Lab


LOINC Code(s)