Laboratory Services
Factor VIII Activity
Print this pageUpdated Test Information:
| Test Description |
Factor VIII Activity
|
|
|---|---|---|
| Synonym(s) |
F8, Factor 8, Factor VIII, UOW1504 |
|
| Test ID |
F8
|
|
| General Information |
Clinical assay interference and limitations: Patients on hirudin (Refludan), bivalrudin (Angiomax), Dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa) and argatroban (Novastan) may show prolonged clotting times. This may cause an under- estimation of the factor concentrations. Emicizumab (Hemlibra) will affect all PTT-based assays and will overestimate the factor concentrations. Certain extended half-life formulation of recombinant Factor VIII may give unreliable results with various Factor VIII assays. |
|
| Container Type |
3 or 5 mL Blue Top (Citrate) Tube |
|
| Specimen Type |
Plasma |
|
| Specimen Requirements |
The Laboratory MUST process specimen, within 4 hrs of blood collection. |
|
| Specimen Collection / Processing Instructions |
Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry ice. |
|
| Department (code) |
Coagulation |
|
| Methodology |
Stago STA Clottable PTT-based Factor Assay |
|
| Testing Schedule |
Monday - Friday |
|
| CPT Code(s) |
85240 |
|
| Reference Range |
Units: % Male/Female: 50-200 |
|
| STAT Orderable (Y/N) |
Yes |
|
| Performing Lab |
UW |
|
| LOINC Code(s) |
3209-4 |
