Laboratory Services

Hepatitis B e-Antibody, Serum

Name: Incyte Diagnostics
Address: 13103 E Mansfield Ave, Spokane Valley, Washington, 99216, USA
Telephone: +1-If-you-have-questions-regarding-your-bill-or-would-like-to-make-a-payment,-please-visit-our-Billing-page-by-clicking-"Pay-Online"-at-the-top-of-the-page-For-other-inquiries,-please-call-us-at-509-892-2700

Updated Test Information:

Test Description	Hepatitis B e-Antibody, Serum
Synonym(s)	Antibody to Hepatitis Be antigen; Hepatitis Be antibody; Anti-HBe; HBe Ab; Hepatitis Be Ab; HEAB
Test ID	HEAB
General Information	Useful for: Determining infectivity of hepatitis B virus (HBV) carriers Monitoring infection status of individuals with chronic hepatitis B Monitoring serologic response of chronically HBV-infected patients receiving antiviral therapy Determining the level of hepatitis B e-antibody See HBV Infection–Diagnostic Approach and Management Algorithm See Viral Hepatitis Serologic Profiles
Specimen Type	Serum
Specimen Requirements	Serum Gel (SST)
Specimen Collection / Processing Instructions	Patient Preparation: For 24 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins
Minimum Sample Volume	0.5 mL
Required Information	Date of collection is required Send separate vials If ordered with HBVQN / Hepatitis B Virus (HBV) DNA Detection and Quantification by Real-Time PCR
Stability	Frozen (preferred): 28 days Refrigerated: 7 days Ambient: 24 hours
Unacceptable Specimen Conditions	Gross hemolysis Gross lipemia Gross icterus
Limitations	Biotin (vitamin B7) is a common ingredient in multivitamins and dietary supplements to enhance hair, nail, and skin growth. Biotin can interfere with the assay performance and cause possible false-negative hepatitis B e-antigen (HBeAg) and false-positive HBe antibody (anti-HBe) results. Patients should be instructed to stop taking such multivitamins and dietary supplements for at least 24 hours prior to blood collection Appearance of anti-HBe in serum does not completely rule-out chronic hepatitis B carrier state or infectivity Performance characteristics of this assay have not been established in patients under the age of 2 or in populations of immunocompromised or immunosuppressed patients. This assay is not licensed by FDA for testing cord blood samples or screening donors of blood, plasma, human cell, or tissue products Performance characteristics have not been established for the following specimen characteristics: Grossly icteric (total bilirubin level of >20 mg/dL) Grossly lipemic (triolein level of >3000 mg/dL) Grossly hemolyzed (hemoglobin level of >124 mg/dL)
Methodology	Chemiluminescence Immunoassay
Estimated TAT	1-2 days
Testing Schedule	Monday-Saturday
Retention	14 days
CPT Code(s)	86707
Reference Range	Negative
Performing Lab	Mayo
LOINC Code(s)	33463-1
Additional Information	Test Definition: HEAB HBV Infection–Diagnostic Approach and Management Algorithm Viral Hepatitis Serologic Profiles