Test Directory

HLA-B27, Blood

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Updated Test Information:

Test Description
HLA-B27, Blood
Synonym(s)

B27; Histocompatibility Antigen; Human Leukocyte Antigen; Leukocyte Antigens; LY27; Spondylitis; W-27 (HLA-B27)

Test ID
LY27B
General Information

Useful for diagnosis of ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter syndrome

Specimen Type

Whole Blood

Specimen Requirements

Lavender top (EDTA)

Additional Processing Details

Specimen must arrive within 96 hours of draw

Stability

Ambient: 4 days

Unacceptable Specimen Conditions

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Limitations

  • Orders received for both this test and SSO1 / HLA Class I Molecular Phenotype, Blood or DISI / HLA Class I Molecular Typing Disease Association (which provides data on all HLA Class I low-resolution antigens, including B27) will be questioned due to test overlap. This HLA-B27 test is best used alone if a particular disease such as ankylosing spondylitis is under consideration

  • Extreme temperature changes during shipping may alter the specimen making it unacceptable for testing

Methodology

Flow Cytometry

Estimated TAT

2-6 days

Testing Schedule

Monday-Saturday

Retention

7 days

CPT Code(s)

86812

Additional Information
Minimum Sample Volume

1 mL

Reference Range

An interpretive report will be provided

Performing Lab

Mayo

LOINC Code(s)

26028-1, 69052-9