Test Directory

Human T-Cell Lymphotropic Virus Types I and II Antibody Screen with Confirmation, Serum

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Updated Test Information:

Test Description
Human T-Cell Lymphotropic Virus Types I and II Antibody Screen with Confirmation, Serum
Synonym(s)

HTLV; HTLV-1; HTLV-2; HTLV Ab; HTLV antibody; HTLV-1 Antibody; HTLV-2 Antibody; HTLV-1 Ab; HTLV-2 Ab

Test ID
HTLVI
General Information

Useful for:



  • Qualitative detection of human T-cell lymphotropic virus types I and II (HTLV-I and HTLV-II)-specific antibodies with confirmation and differentiation between HTLV-I and HTLV-II infection

  • This test is for serum specimens only

    • For spinal fluid, order HTLVC / Human T-Cell Lymphotropic Virus Types 1 and 2 (HTLV-1/-2) Antibody Screen with Confirmation, Spinal Fluid



  • This test is not intended for screening blood, human cells, tissues, or solid-organ donors

  • This test is not intended for use on cord blood specimens.

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel (SST)

  • Acceptable: Red Top

Additional Processing Details

  • Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge within 2 hours of collection for BD Vacutainer tubes)

  • Aliquot serum into plastic vial

Required Information

Date of collection is required

Stability

  • Frozen (preferred): 28 days

  • Refrigerated: 7 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

Limitations

  • This test is not offered as a screening or confirmatory test for serum specimens from blood, human cells, tissues, or solid organ donors

  • A negative test result does not exclude the possibility of exposure to human T-cell lymphotropic virus types I and II (HTLV-I or HTLV-II). Levels of total antibodies to these viruses may be undetectable in early infection

  • Performance characteristics have not been established for the following specimen characteristics:

    • Grossly icteric (total bilirubin >20 mg/dL)

    • Grossly lipemic (triolein >3000 mg/dL)

    • Grossly hemolyzed (hemoglobin >3051 mg/dL)

    • Containing particulate matter

    • Cadaveric specimens



Methodology

Enzyme Immunoassay (EIA)

Estimated TAT

1-4 days

Testing Schedule

Monday-Friday

Retention

14 days

CPT Code(s)

86790

Additional Information
Minimum Sample Volume

0.6 mL

Reference Range

Negative

Reflex Conditions

HTLV-I/-II Ab Confirmation (HTLVL)

Performing Lab

Mayo

LOINC Code(s)

29901-6