Test Directory

Insulin-Like Growth Factor-Binding Protein 3 (IGFBP-3), Serum

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Updated Test Information:

Test Description
Insulin-Like Growth Factor-Binding Protein 3 (IGFBP-3), Serum
Synonym(s)
IGFBP-3
Test ID
IGFB3
General Information
Useful for:
Diagnosing growth disorders
Diagnosing adult growth hormone deficiency
Monitoring of recombinant human growth hormone treatment
As a possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of acromegaly and gigantism
Specimen Type
Serum
Specimen Requirements
SST
Additional Processing Details
0.3 mL
Stability
Frozen (preferred) 14 days
Refrigerated 24 hours
Unacceptable Specimen Conditions
Gross hemolysis Reject
Gross lipemia OK
Methodology
Enzyme-Labeled Chemiluminescent Immunometric Assay
Estimated TAT
1-3 days
Testing Schedule
Monday-Saturday
CPT Code(s)
83520
Reference Range

1-7 days: < or =0.7 mcg/mL
8-14 days: 0.5-1.4 mcg/mL
15 days-11 months: unavailable
1 year: 0.7-3.6 mcg/mL
2 years: 0.8-3.9 mcg/mL
3 years: 0.9-4.3 mcg/mL
4 years: 1.0-4.7 mcg/mL
5 years: 1.1-5.2 mcg/mL
6 years: 1.3-5.6 mcg/mL
7 years: 1.4-6.1 mcg/mL
8 years: 1.6-6.5 mcg/mL
9 years: 1.8-7.1 mcg/mL
10 years: 2.1-7.7 mcg/mL
11 years: 2.4-8.4 mcg/mL
12 years: 2.7-8.9 mcg/mL
13 years: 3.1-9.5 mcg/mL
14 years: 3.3-10 mcg/mL
15 years: 3.5-10 mcg/mL
16 years: 3.4-9.5 mcg/mL
17 years: 3.2-8.7 mcg/mL
18 years: 3.1-7.9 mcg/mL
19 years: 2.9-7.3 mcg/mL
20 years: 2.9-7.2 mcg/mL
21-25 years: 3.4-7.8 mcg/mL
26-30 years: 3.5-7.6 mcg/mL
31-35 years: 3.5-7.0 mcg/mL
36-40 years: 3.4-6.7 mcg/mL
41-45 years: 3.3-6.6 mcg/mL
46-50 years: 3.3-6.7 mcg/mL
51-55 years: 3.4-6.8 mcg/mL
56-60 years: 3.4-6.9 mcg/mL
61-65 years: 3.2-6.6 mcg/mL
66-70 years: 3.0-6.2 mcg/mL
71-75 years: 2.8-5.7 mcg/mL
76-80 years: 2.5-5.1 mcg/mL
81-85 years: 2.2-4.5 mcg/mL

Tanner Stages:

Males
Stage I 1.4-5.2 mcg/mL
Stage II 2.3-6.3 mcg/mL
Stage III 3.1-8.9 mcg/mL
Stage IV 3.7-8.7 mcg/mL
Stage V 2.6-8.6 mcg/mL
Females
Stage I 1.2-6.4 mcg/mL
Stage II 2.8-6.9 mcg/mL
Stage III 3.9-9.4 mcg/mL
Stage IV 3.3-8.1 mcg/mL
Stage V 2.7-9.1 mcg/mL

Note: Puberty onset, ie, the transition from Tanner stage I (prepubertal) to Tanner stage II (early pubertal), occurs for girls at a median age of 10.5 (+/-2) years and for boys at a median age of 11.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. By contrast, for boys there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (young adult) should be reached by age 18.

Performing Lab
Mayo
LOINC Code(s)
2483-6