Laboratory Services
Metanephrines, Fractionated, Free, Plasma
Print this pageUpdated Test Information:
| Test Description |
Metanephrines, Fractionated, Free, Plasma
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|---|---|---|
| Synonym(s) |
UOW2604, Fractionated Metanephrines-Plasma, Free Metanephrines-Plasma, MEN, MEN IIA, MEN IIB, Multiple Endocrine Neoplasia, Neuroendocrine, NMN (Normetanephrines)-plasma, paraganglioma, Phaeochromocytoma, Pheochromocytoma, Soft-PMET |
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| Test ID |
PLMET
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| General Information |
The most sensitive test to rule-out pheochromocytoma is plasma free metanephrines (PLMET). See also Metanephrines, Fractionated, Urine (RUFMET). For a recent review of the biochemical diagnosis of pheochromocytoma, see Pacak K et al. Nature Clin Pract Endocrinol Metab 2007; 3:92-102.PMID: 17237836 The concentration of metanephrine and normetanephine is determined by solid phase extraction followed by liquid chromatography-tandem mass spectrometry. The reportable range is 0.2 to 80.0 nmol/L for metaneprhine and normetaneprhine, respectively, with imprecision between 3.3 and 8.2 %CV. |
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| Container Type |
3mL blood in a LAVENDER TOP (EDTA) tube |
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| Specimen Type |
Plasma |
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| Specimen Requirements |
1.5 mL EDTA plasma |
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| Specimen Collection / Processing Instructions |
Centrifuge & remove plasma - Freeze in plastic aliquot tube at -20˚C. |
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| Minimum Sample Volume |
0.5 mL EDTA plasma |
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| Department (code) |
Chemistry, University |
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| Methodology |
Serum solid phase extraction. Isotope dilution liquid chromatography mass spectrometry |
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| Testing Schedule |
Monday |
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| Test Includes |
MN Metanephrine |
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| CPT Code(s) |
83835 |
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| STAT Orderable (Y/N) |
No |
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| Performing Lab |
UW |
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| LOINC Code(s) |
