Laboratory Services

Methylmalonic Acid, Quantitative, Serum

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Updated Test Information:

Test Description
Methylmalonic Acid, Quantitative, Serum

MMA1, UOW3442

Test ID
General Information

Methylmalonic acid in serum is measured by ultrafitration and liquid chromatography-tandem mass spectrometry. The reportable range is 0.1 - 5 mcmol/L with imprecision of 4.5 %CV.

Specimen Type


Alternate Specimen Type

4 mL blood in RED TOP tube

Specimen Requirements

4 mL blood in SST tube

Specimen Collection / Processing Instructions

Centrifuge and separate serum as soon as possible and refrigerate.

Note: Serum needs to be removed from Red top and any Separator tube.

Minimum Sample Volume

requested: 0.5 mL serum
minimum: 0.25 mL serum


Refrigerated: 7 days


HPLC - Tandem Mass Spectrometry

Testing Schedule

Monday, Thursday

Test Includes

Methylmalonic Acid - MMA
Methylmalonic Acid Method - MMAM

CPT Code(s)


Reference Range

Elevated >0.30 mcmol/L

Performing Lab

UW Laboratory

LOINC Code(s)