Laboratory Services

MMRV Immune Status Profile, Serum

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Updated Test Information:

Test Description
MMRV Immune Status Profile, Serum
Synonym(s)

Immunity Panel; Measles (Rubeola) Ab, IgG, Serum; Mumps Ab, IgG, Serum; Rubella Ab, IgG, Serum; Varicella-Zoster Ab, IgG, Serum

Test ID
MMRV
General Information

Useful for:



  • Determination of immune status of individuals to measles, mumps, rubella, and varicella-zoster viruses (VZV)

  • Documentation of previous infection with measles, mumps, rubella, or VZV in an individual without a previous record of immunization to these viruses

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel (SST)

  • Acceptable: Red Top

Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 14 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat-inactivated specimen

Limitations

  • IgG-class antibodies to measles, mumps, rubella, or varicella-zoster virus may be present in serum specimens from individuals who have received blood products within the past several months but have not been immunized or experienced past infection with this virus

  • Specimens drawn early during the acute phase of infection or shortly (1-2 weeks) following vaccination may be negative for IgG-class antibodies.

Methodology

Multiplex Flow Immunoassay (MFI)

Estimated TAT

1 day

Testing Schedule

Monday-Saturday

Test Includes

  • ROPG: Measles (Rubeola) Ab, IgG

  • MPPG: Mumps Ab, IgG

  • RBPG: Rubella Ab, IgG

  • VZPG: Varicella-Zoster Ab, IgG

CPT Code(s)

86735; 86762; 86765; 86787

Additional Information
Minimum Sample Volume

0.4 mL

Reference Range
Antibody Index: AI Measles (AI) Mumps (AI) Varicella (AI) Rubella (AI)
Vaccinated: Positive ≥ 1.1 ≥ 1.1 ≥ 1.1 ≥ 1.0
Unvaccinated: Negative ≤ 0.8 ≤ 0.8 ≤ 0.8 ≤ 0.7
Performing Lab

Mayo

LOINC Code(s)

15410-4, 40667-8, 6476-6, 35275-7, 5244-9, 52986-7, 25418-5, 5403-1