Laboratory Services

NTx Telopeptide, Urine (Sendout)

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Updated Test Information:

Test Description
NTx Telopeptide, Urine (Sendout)

0070062, Collagen Crosslinks, Crosslinked N-telopeptide of Type I Collagen (NTX), N-Telopeptide, NTX Creatinine, Osteomark, Osteoporosis, UNTPG, Urine, UOW4797

Test ID
General Information

Useful For: As an adjunct in the diagnosis of medical conditions associated with increased bone turnover
Monitoring effectiveness of antiresorptive therapy in patients treated for osteopenia, osteoporosis, Paget disease, or other metabolic bone disorders
For monitoring therapy, a baseline specimen should be collected prior to initiation of therapy. Subsequent specimens for comparison should be collected at the same time of day as the baseline specimen.

Container Type

Sterile Urine Cup

Specimen Type


Specimen Requirements

1 mL urine

Specimen Collection / Processing Instructions

Random Collection: Collect second-morning void urine in a screw-cap, urine collection container without preservative.

Timed Collection:

Collect urine for 24 hours in a preservative-free amber polyethylene 24-hr urine collection container.
Refrigerate sample during collection.
Record the collection interval.

Minimum Sample Volume

0.5 mL

Required Information

24 hour collections must provide the duration and total volume collected.


Frozen (preferred) - 4 weeks
Refrigerated - 1 week
Ambient - 24 hours

Unacceptable Specimen Conditions

Specimens contaminated with blood or extensive hemolysis


Quantitative Chemiluminescent Immunoassay (CLIA)

Estimated TAT

1-4 Days

Testing Schedule

Tuesday - Saturday

CPT Code(s)


Reference Range


7-9 years: 167-578 nM BCE/mM creatinine
10-12 years: 152-505 nM BCE/mM creatinine
13-15 years: 103-776 nM BCE/mM creatinine
16-17 years: 34-313 nM BCE/mM creatinine
18 years and older: 21-83 nM BCE/mMcreatinine

7-9 years: 201-626 nM BCE/mM creatinine
10-12 years: 173-728 nMBCE/mM creatinine
13-15 years: 38-515 nM BCE/mM creatinine
16-17 years: 20-144 nM BCE/mMcreatinine
Premenopausal: 17-94 nM BCE/mM creatinine
Postmenopausal: 26-124 nM BCE/mM creatinine

STAT Orderable (Y/N)


Performing Lab

UW (sendout to ARUP)

LOINC Code(s)