Laboratory Services

Nuclear Magnetic Resonance Lipoprotein Profile, Serum

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Updated Test Information:

Test Description
Nuclear Magnetic Resonance Lipoprotein Profile, Serum
Synonym(s)

HDL particle number; HDL particles; LDL Cholesterol; LDL particle number; LDL particles; Lipoprotein particles; NMR; NMRLP; NMR profile; Nuclear magnetic resonance

Test ID
NMRLP
Performing Lab

Labcorp

General Information

Useful for:



  • Assessment and management of a patient's risk for atherosclerotic cardiovascular disease

  • Identifying residual risk that may be present in some patients on cholesterol targeting treatment

Container Type

NMR LipoTube (black-and-yellow-top tube) is the preferred container, plain red-top tube, lavender-top (EDTA-no gel) tube, OR green-top (heparin-no gel) tube.

Specimen Type

Spun NMR LipoTube (preferred), serum from a plain red-top tube, plasma from a lavender-top (EDTA-no gel), OR green-top (heparin-no gel) tube. Keep refrigerated and SHIP WITH FROZEN COOL PACKS.

Specimen Requirements

Red Top

Specimen Collection / Processing Instructions

  • Patient Preparation:

    • Fasting overnight (12-14 hours) is required. On night before examination, evening meal should be eaten before 6 p.m. and should contain no fatty foods

    • Patient must not consume any alcohol for 24 hours before the specimen is collected



  • Collection Instructions:

    • Allow isopropyl alcohol (from phlebotomy site prep) to dry thoroughly before venipuncture

    • Centrifuge and aliquot serum



Minimum Sample Volume

1 mL

Stability

Refrigerate all acceptable tube types as soon as possible after centrifugation and within 24 hours of collection. Keep refrigerated prior to shipment, and SHIP ON FROZEN COOL PACKS. Do NOT store at room temperature. Do NOT freeze the sample. Sample is stable refrigerated for six days.

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

Limitations

Failure to follow specimen collection requirements may prevent measurable results

Methodology

Nuclear Magnetic Resonance (NMR)

Estimated TAT

2-7 days

Testing Schedule

Tuesday and  Friday

Test Includes

  • LDL Particles

  • HDL Particles

  • LDL Cholesterol (NMR)

Retention

7 days

CPT Code(s)

83704

Reference Range
Gender HDL Particles (mcmol/L)
Male > 30
Female > 35
Range LDL Particles (nmol/L) LDL Cholesterol (NMR): (mg/dL)
Desirable < 1000 < 100
Above Desirable 1000 - 1299 100 - 129
Borderline High 1300 - 1599 130 - 159
High 1600 - 1999 160 - 189
Very High ≥ 2000 ≥ 190


Reference values have not been established for patients who are <18 years of age.

LOINC Code(s)

54434-6, 49748-7, 2089-1

Additional Information