Laboratory Services
Protein S Activity, Clot
Print this pageUpdated Test Information:
Test Description |
Protein S Activity, Clot
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Synonym(s) |
UOW1155, Protein S-Clot Based |
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Test ID |
PSCLOT
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General Information |
Patients on direct thrombin inhibitors such as bivalirudin (Angiomax), dabigatran (Pradaxa), argatroban (Novastan) or anti-Xa drugs such as rivaroxaban (Xarelto), apixaban (Eliquis) and edoxaban (Savaysa), may lead to an over-estimation of the protein S level with this assay. Recommend Free Protein S Antigen assay if the patient is taking direct oral anticoagulants. Patients on coumadin therapy may see decrease in protein S activity because of the vitamin K antagonistic effect of the drug. Protein S is a vitamin K dependent factor. Protein S activity may be decreased in the setting of acute phase responses. Outside clients should fill and submit Coagulation Patient Clinical History Form. |
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Container Type |
3 or 5 mL Blue Top (CITRATE) tube |
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Specimen Type |
Plasma |
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Specimen Requirements |
The Laboratory MUST process specimen, within 4 hrs of blood collection. |
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Specimen Collection / Processing Instructions |
Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry ice. |
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Department (code) |
Coagulation |
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Methodology |
Stago Staclot Protein S Assay |
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Testing Schedule |
Thursday |
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CPT Code(s) |
85306 |
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Reference Range |
Units: % Male/Female 0-2m 15-150 3m-5m 35-150 6m-11m 47-150 1y-5y 49-150 6y-9y 58-150 10y- 65-150
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STAT Orderable (Y/N) |
No |
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Performing Lab |
UW |
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LOINC Code(s) | ||
Collection File | View/Download File |