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QuantiFERON-TB Gold Plus

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Updated Test Information:

Test Description
QuantiFERON-TB Gold Plus
Synonym(s)

IGRA-TB, interferon gamma release assay to tuberculosis antigens, QFT, Quantafluor TB, Quantiferon TB-gold, Quantiferon TB-gold Plus, UOW3622
Test ID
QFTB4
Performing Lab

Labcorp
General Information

This test is for the diagnosis of latent TB (tuberculosis) infection.
Container Type

The QuantiFERON(R)-TB Gold Plus collection kit contains the instructions for the collection and handling of (one each): (1) gray-top (with white ring), uncoated (nil); (2) green cap with white ring, TB1 tube; (3) yellow cap with white ring, TB2 tube; (4) purple top with white ring, mitogen-coated. A high altitude kit is also available for locations between 3350 and 6150 feet; a cap with a yellow ring differentiates the tubes.
Specimen Type

Whole Blood
Specimen Requirements

Preferred: 5 mL Lithium-Heparin whole blood


ALTERNATE: 1 mL whole blood in each of the QuantiFERON TB Gold PLUS (4 tube set) tubes
Alternate Specimen Type

QuantiFERON TB Gold PLUS (4 tube set)


THE ALTERNATE SPECIMEN TYPE IS ONLY AVAILABLE TO LOCATIONS THAT CAN PROCESS AS LISTED IN THE "Specimen Collection/Processing Instructions" BELOW
Specimen Collection / Processing Instructions

Preferred: Collect 5 mL Lithium-Heparin in a 7 mL non-gel tube (if using 4 mL Lithium-Heparin non-gel tubes collect 2 full tubes), Transport tube(s) refrigerated within 40 hours of collection. Friday collections should be received the same day of collection due to weekend operating hours.


Alternate: This method is only available to locations that can process as follows: 1. Collect 1 mL minimum in each of the QuantiFERON TB Gold PLUS (4 tube set) tubes. 2. Incubate the QuantiFERON TB Gold PLUS (4 tube set) within 16 hours of collection for 16-24 hours. 3. Centrifuge the incubated QuantiFERON TB Gold PLUS (4 tube set) tubes for 15 minutes at 2,000-3,000 RCF (g). 4. Transport incubated/centrifuged QuantiFERON TB Gold PLUS tubes refrigerated.
Minimum Sample Volume

Preferred: 5 mL Lithium-Heparin whole blood non-gel tube


Alternate: 1 mL whole blood in each QuantiFERON TB Gold PLUS (4 tube set)
Stability

Green top whole blood – refrigerated
and  4 tube QFT Gold Tube collection Kit - Room temp 16 hours
Unacceptable Specimen Conditions

Lithium-Heparin Gel separator tubes, Gross Hemolysis, Gross Lipemia, Gross Icterus, Alternate method submitted not following processing instructions
Department (code)

Virology
CPT Code(s)

86480
Reflex Conditions

No
STAT Orderable (Y/N)

No
LOINC Code(s)