Sjogren's Syndrome

Sjogren's Syndrome

Anti-SSB/La, Anti-SSA/Ro

SJO

The presence of both SS-A/Ro and SS-B/La antibodies are highly specific serological markers for the diagnosis and disease management of patients with Sjögren’s syndrome or lupus patients with Sjögren's overlap syndrome. SS-A/Ro antibodies can be a marker for SLE and Sjögren’s syndrome. SS-B/La antibodies are highly specific clinical markers for Sjögren’s syndrome, but a small proportion of patients can remain SS-B/La negative. Assay results should be used in conjunction with clinical findings and other serological tests.

Serum

Plasma (Li-Heparin, EDTA, or Citrate)

Tiger

1.5 mL

750 uL

Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.

Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.

Lipemic, hemolyzed or microbially contaminated samples.

Fluorescent enzyme immunoassay (FEIA)

2-5 days

Monday-Saturday, alternating days

SS-A/Ro
SS-B/La

86235x2

Incyte Diagnostics

33610-7, 33613-1